Lead Level in Pregnant Women Suffering from Pre-eclampsia in Dakahlia, Egypt

SM Motawei, SM Attalla, HE Gouda, MA El-Harouny, AM El-Mansoury


Background: Lead toxicity is a prevalent health problem in both developed and developing countries. One of the proposed mechanisms for lead-induced organ damage is oxidative stress. Oxidative stress is well-associated with the pregnancy disorder, pre-eclampsia. Exposure to lead may be one of the sources of the oxidative stress that leads to development of pre-eclampsia in pregnant women.

Objective: To test if blood lead level of pregnant women suffering from pre-eclampsia is higher than the normal limit. Methods: Using atomic absorption spectrophotometry, blood lead level was measured in 115 pregnant women suffering from pre-eclampsia and compared to its level in a comparison group of 25 healthy pregnant women in Dakahlia governorate, Egypt.

Results: The mean±SD blood lead level was 37.68±9.17 μg/dL in women with pre-eclampsia; the value in the comparison group was 14.5±3.18 μg/dL (p<0.001).

Conclusion: Pre-eclampsia is significantly associated with a high blood lead level.


Lead poisoning; Pre-eclampsia; Pregnancy complications

 pISSN: 2008-6520
 eISSN: 2008-6814

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