Intestinal Obstruction in Acute Inhalational Toluene 2,4-Diisocyanate Gas Toxicity

S Shadnia, M Ahmadimanesh, M Ghazi-Khansari, N Zamani


The isocyanates are widely used as precursors of polyurethane products, as well as carbamate insecticides. Toluene 2,4-diisocyanate (TDI) is one of the most important commercially used isocyanates. Humans may be exposed to TDI by inhalation, ingestion, dermal and eye contact. TDI is a powerful irritant to the mucosal membranes of the gastrointestinal and respiratory tracts, eyes and the skin. Pulmonary manifestations, especially occupational asthma, are the predominant manifestations after TDI toxicity. Herein, we present intestinal obstruction as an extraordinary manifestation of acute TDI toxicity after occupational exposure. TDI toxicity may cause intestinal obstruction.


Intestinal obstruction; Toluene 2,4 diisocyanate; Intestinal obstruction; General surgery; Toxicity

 pISSN: 2008-6520
 eISSN: 2008-6814

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